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The Lexus RX 350 is available in front-wheel and all-wheel drive configurations, powered by a 2.4L turbocharged 4-cylinder engine producing 275 horsepower paired with an 8-speed automatic transmission. The all-wheel drive 350h utilizes a 2.5L 4-cylinder engine generating 183 horsepower connected to a CVT transmission, while the all-wheel drive RX 500h features a 2.4L turbocharged 4-cylinder engine delivering 274 horsepower through a 6-speed automatic transmission. The new 450h+ combines a 2.5L turbocharged 4-cylinder with two electric motors for a total system output of 304 horsepower. The RX 350 and RX 350h are offered with four trim levels: Base, Premium, Premium Plus, Luxury and F Sport Design. The 450h+ is available with the Luxury trim while the RX 500h is offered in the F Sport Performance trim. The base model includes paddle shifters, power liftgate, reverse tilt-down heated mirrors, 19-inch aluminum wheels, 8 airbags, auto-dimming rearview mirror, 8-way heated power front seats, leatherette upholstery, cargo cover, dual-zone automatic climate control with separate rear controls, satellite radio, 12-speaker audio system, Apple CarPlay and Android Auto integration, a 9.8-inch touchscreen, 6 USB ports, proximity keyless entry with push-button start, remote start, vehicle tracking system, leather-wrapped steering wheel with power tilting and telescoping adjustment, power windows with one-touch operation, and rain-sensing wipers. The RX 450h+ plug-in hybrid achieves an estimated 35 MPG combined and features a lithium-ion battery for extended electric driving capability. The 350h hybrid delivers an impressive 36 MPG combined, while the standard RX 350 manages 25 MPG combined in front-wheel drive configuration and 24 MPG with all-wheel drive. The performance-oriented RX 500h provides a respectable 27 MPG combined despite its enhanced power output. Performance capabilities vary by powertrain, with the RX 500h F Sport Performance achieving the quickest acceleration at 5.9 seconds from 0-60 mph, followed by the RX 450h+ at 6.2 seconds. The RX 350 with all-wheel drive reaches 60 mph in 7.2 seconds, with the 350h completing the sprint in 7.4 seconds. The RX 500h F Sport Performance enhances the driving experience with an auto-leveling suspension, 21-inch wheels, heated and ventilated front bucket seats, sport pedals, an auto tilt-away power sport steering wheel, a 12.3-inch configurable digital gauge cluster, and a 14-inch touchscreen display. Every 2025 RX model comes standard with the comprehensive Lexus safety system+ 3.0, wireless Apple CarPlay and Android Auto integration, and connected services including safety connect, service connect, and remote connect with multi-year trial periods. Available safety features across all models include the Lexus safety system+, a pre-collision system with automated braking and pedestrian detection, rear collision warning, driver attention alert, traffic sign recognition, lane departure alert with steering assist, vehicle sway warning, a rear-view camera, all-speed dynamic radar cruise control with traffic stop-go functionality, and Intelligent high beam automatic LED headlights.
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